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David K C Cooper Selected Research

Heterologous Transplantation (Xenotransplantation)

10/2022Will previous palliative surgery for congenital heart disease be detrimental to subsequent pig heart xenotransplantation?
1/2022Serum Antibody Binding and Cytotoxicity to Pig Cells in Chinese Subjects: Relevance to Clinical Renal Xenotransplantation.
1/2022Current Topics of Relevance to the Xenotransplantation of Free Pig Islets.
1/2021Potential roles of mesenchymal stromal cells in islet allo- and xenotransplantation for type 1 diabetes mellitus.
1/2021Immunological selection and monitoring of patients undergoing pig kidney transplantation.
1/2021Pig kidney xenotransplantation: Progress toward clinical trials.
1/2021The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure.
1/2021A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation.
11/2020The immune system in infants: Relevance to xenotransplantation.
1/2020How the COVID-19 pandemic may impact public support for clinical xenotransplantation in the United States?
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David K C Cooper Research Topics

Disease

18Inflammation (Inflammations)
01/2021 - 09/2015
15Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2022 - 01/2008
13Brain Death (Brain Dead)
11/2021 - 08/2005
13Infections
01/2021 - 06/2003
11Thrombocytopenia (Thrombopenia)
01/2022 - 11/2011
11Thrombotic Microangiopathies
01/2018 - 07/2003
6Thrombosis (Thrombus)
10/2019 - 11/2003
5Congenital Heart Defects (Congenital Heart Defect)
10/2022 - 01/2017
4Acute Liver Failure (Fulminant Hepatic Failure)
01/2022 - 11/2009
4Chronic Kidney Failure (Chronic Renal Failure)
01/2022 - 01/2019
4Lymphoproliferative Disorders (Lymphoproliferative Disorder)
01/2019 - 05/2004
2Hypertrophy
01/2021 - 01/2012
2Hypoplastic Left Heart Syndrome
11/2020 - 02/2019
2Reperfusion Injury
01/2020 - 01/2019
2Neoplasms (Cancer)
01/2019 - 09/2002
2Blindness (Hysterical Blindness)
11/2015 - 03/2014
2Corneal Diseases (Corneal Disease)
05/2014 - 03/2014
2Hemorrhage
01/2012 - 07/2003
2Disseminated Intravascular Coagulation
11/2006 - 11/2003
2Graft vs Host Disease (Graft-Versus-Host Disease)
05/2006 - 12/2004
1Cytokine Release Syndrome
07/2022
1Sickle Cell Anemia (Hemoglobin S Disease)
11/2021
1Anemia
01/2021
1Hypovolemia
01/2021
1Heart Failure
01/2021
1Hypothermia
12/2020
1COVID-19
01/2020
1Zoonoses
01/2020
1Corneal Opacity
11/2019
1Vasculitis (Vasculitides)
10/2019
1Frailty
01/2019
1Burns
11/2018
1Wounds and Injuries (Trauma)
10/2017
1Hepatitis B
01/2017
1Thromboembolism
01/2017
1Edema (Dropsy)
01/2017
1Fibrosis (Cirrhosis)
01/2017
1Foreign-Body Reaction
11/2016
1Kidney Diseases (Kidney Disease)
08/2016
1Disease Progression
01/2016

Drug/Important Bio-Agent (IBA)

7Insulin (Novolin)FDA Link
11/2016 - 02/2006
6AntibodiesIBA
11/2020 - 05/2004
6Proteins (Proteins, Gene)FDA Link
01/2020 - 06/2003
5Thyroid HormonesIBA
01/2021 - 10/2014
5Fibrinogen (Factor I)FDA Link
10/2019 - 05/2015
4Interleukin-6 (Interleukin 6)IBA
07/2022 - 01/2017
4Triiodothyronine (Liothyronine)FDA LinkGeneric
01/2016 - 10/2014
3Anti-Inflammatory Agents (Anti-Inflammatories)IBA
01/2022 - 01/2019
3AntigensIBA
11/2020 - 06/2009
3Complement System Proteins (Complement)IBA
01/2020 - 01/2018
3CytokinesIBA
01/2019 - 12/2006
3Thyroxine (Levothyroxine)FDA LinkGeneric
01/2015 - 10/2014
3Vasopressins (Vasopressin)IBA
01/2015 - 12/2006
2Immunoglobulin G (IgG)IBA
01/2022 - 08/2013
2Histones (Histone)IBA
01/2020 - 10/2017
2Intravenous Immunoglobulins (IVIG)FDA Link
01/2020 - 11/2013
2Interleukin-17 (Interleukin 17)IBA
01/2017 - 01/2017
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2015 - 11/2014
2Streptozocin (Streptozotocin)FDA Link
01/2014 - 05/2007
2Dacarbazine (DIC)FDA LinkGeneric
11/2006 - 11/2003
2DNA (Deoxyribonucleic Acid)IBA
09/2003 - 05/2002
1Immunoglobulin M (IgM)IBA
01/2022
1Etanercept (Enbrel)FDA Link
01/2021
1CarbohydratesIBA
11/2020
1InterleukinsIBA
01/2020
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2020
1ChemokinesIBA
01/2018
1Oxygen (Dioxygen)IBA
11/2016
1Capsules (Microcapsules)IBA
11/2016
1rho-Associated KinasesIBA
10/2016
1Y 27632IBA
10/2016
1Biomarkers (Surrogate Marker)IBA
08/2016
1MicroRNAs (MicroRNA)IBA
08/2016
1O-(glucuronic acid 2- sulfate)- (1- - 4)- O- (2,5)- anhydromannitol 6-sulfateIBA
01/2016
1Hormones (Hormone)IBA
01/2016
1Blood Glucose (Blood Sugar)IBA
01/2016

Therapy/Procedure

49Heterologous Transplantation (Xenotransplantation)
10/2022 - 05/2002
25Transplantation
01/2022 - 09/2004
18Therapeutics
01/2021 - 07/2003
7Organ Transplantation
01/2020 - 09/2002
6Liver Transplantation
01/2022 - 11/2009
6Islets of Langerhans Transplantation
01/2021 - 05/2007
4Corneal Transplantation (Keratoplasty)
11/2019 - 03/2014
3Heart Transplantation (Grafting, Heart)
01/2022 - 09/2015
3Euthanasia (Mercy Killing)
12/2018 - 01/2012
2Kidney Transplantation
11/2021 - 12/2018
2Operative Surgical Procedures
01/2017 - 01/2016
2Resuscitation
01/2016 - 02/2008
2Cardiopulmonary Bypass (Heart-Lung Bypass)
01/2016 - 10/2014
1Palliative Care (Palliative Therapy)
10/2022
1Renal Dialysis (Hemodialysis)
01/2022
1Artificial Liver (Bioartificial Liver)
01/2022
1Peritoneal Dialysis
01/2022
1Blood Transfusion (Blood Transfusions)
11/2021
1Glycemic Control
01/2021
1Heart-Lung Machine
12/2020
1Immunomodulation
01/2019
1Slit Lamp
01/2017
1Heart-Assist Devices
01/2017
1Drug Therapy (Chemotherapy)
11/2016